Bastante interesante el paper que ha salido hace poco y que James resume en este vídeo.
Systematically Improving Espresso: Insights from Mathematical Modeling and Experiment.
https://www.cell.com/matter/fulltext/S2590-2385(19)30410-2?_returnURL=https%3a%2f%2flinkinghub.elsevier.com%2fretrieve%2fpii%2fS2590238519304102%3fshowall%3dtrue